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Czasopismo
2022 | 8 | nr 4 | 46--57
Tytuł artykułu

Sexual dimophism in plasma nitrogenous metabolites levels and some psycho-neuro-endocrine parameters

Warianty tytułu
Języki publikacji
EN
Abstrakty
EN
Background. We previously showed that the factor structure of the relationships between the plasma levels of nitrogenous metabolites (uric acid, bilirubin, urea, and creatinine), on the one hand, and the parameters of anxiety and neuro-endocrine status, on the other hand, is significantly different in men and women of reproductive age and postmenopausal. The purpose of this study is to identify the metabolic and psycho-neuro-endocrine features of these three cohorts of people. Materials and methods. The object of observation were 31 males (24÷69 y) and 30 females, from among them 18 postmenopausal (45÷76 y) and 12 of reproductive age (30÷42 y), with dysfunction of neuro-endocrine-immune complex. In basal conditions we determined plasma levels of nitrogenous metabolites and adaptation hormones, estimated the severity of the trait and reactive anxiety, recorded the ongoing HRV and EEG. After 4 or 7 days, repeated testing was performed. Results. To achieve the goal, the registered parameters were subjected to discriminant analysis. Along with the quite expected nitrogenous metabolites, age, testosterone and calcitonin (both raw and sex- and age-standardized values), trait anxiety, Kerdö's Vegetative Index, one of the vagal markers (SDNN), as well as 10 EEG parameters emerged as characteristic features of the cohorts. In the information space of two discriminant roots, three cohorts are clearly demarcated. Conclusion. We interpret this as another proof of the existence of connections between nitrogenous metabolites and psycho-neuro-endocrine parameters in line with the concept of the functional-metabolic continuum.(original abstract)
Słowa kluczowe
Czasopismo
Rocznik
Tom
8
Numer
Strony
46--57
Opis fizyczny
Twórcy
  • Ukrainian Scientific Research Institute of Medicine of Transport, Odesa, Ukraine
  • Ukrainian Scientific Research Institute of Medicine of Transport, Odesa, Ukraine
  • Ukrainian Scientific Research Institute of Medicine of Transport, Odesa, Ukraine;
  • Donets'kian National Medical University, Kropyvnyts'kyi, Ukraine
autor
  • Nicolaus Copernicus University in Torun, Torun
Bibliografia
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Typ dokumentu
Bibliografia
Identyfikatory
Identyfikator YADDA
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